This short TED talk doesn't need much introduction. His quote at the end is one of my favorites of all time:
"Nothing is so dangerous to the progress of the human mind than to assume that our views of science are ultimate. That there are no mysteries in nature, that our triumphs are complete, and that there are no new worlds to conquer"
Another great example of how pushing the boundries of what can and cannot be done breaks something and why it's important to soldier on anyway.